What prion disease is linked with cannibalistic practices?

Kuru is a neurodegenerative disorder that is classified as a prion disease and is historically associated with cannibalistic practices, particularly among the Fore people of Papua New Guinea. The disease is transmitted through the consumption of infected human brain tissue, as prions can be present in the neural tissue of individuals who have the disease. Kuru is characterized by symptoms such as tremors, loss of coordination, and ultimately leads to severe neurological decline and death.

The link to cannibalism is significant because it illustrates how prion diseases can be spread through specific cultural practices, allowing for the transmission of these misfolded proteins in a way that might not occur in environments where such practices are not present. Understanding Kuru provides insight into the role of prions in disease and how societal behaviors can impact health outcomes in unique ways.